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Year | Number of Results |
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2021 | 2 |
2023 | 3 |
2024 | 2 |
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Page 1
Pyruvate anaplerosis is a targetable vulnerability in persistent leukaemic stem cells.
Nat Commun. 2023 Aug 17;14(1):4634. doi: 10.1038/s41467-023-40222-z.
Nat Commun. 2023.
PMID: 37591854
Free PMC article.
Arginine dependency is a therapeutically exploitable vulnerability in chronic myeloid leukaemic stem cells.
Rattigan KM, Zarou MM, Brabcova Z, Prasad B, Zerbst D, Sarnello D, Kalkman ER, Ianniciello A, Scott MT, Dunn K, Shokry E, Sumpton D, Copland M, Tardito S, Vande Voorde J, Mussai F, Cheng P, Helgason GV.
Rattigan KM, et al. Among authors: zarou mm.
EMBO Rep. 2023 Oct 9;24(10):e56279. doi: 10.15252/embr.202256279. Epub 2023 Jul 25.
EMBO Rep. 2023.
PMID: 37489735
Free PMC article.
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Folate metabolism: a re-emerging therapeutic target in haematological cancers.
Zarou MM, Vazquez A, Vignir Helgason G.
Zarou MM, et al.
Leukemia. 2021 Jun;35(6):1539-1551. doi: 10.1038/s41375-021-01189-2. Epub 2021 Mar 11.
Leukemia. 2021.
PMID: 33707653
Free PMC article.
Review.
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Metabolism in stem cell-driven leukemia: parallels between hematopoiesis and immunity.
Rattigan KM, Zarou MM, Helgason GV.
Rattigan KM, et al. Among authors: zarou mm.
Blood. 2023 May 25;141(21):2553-2565. doi: 10.1182/blood.2022018258.
Blood. 2023.
PMID: 36634302
Free PMC article.
Review.
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Inhibition of mitochondrial folate metabolism drives differentiation through mTORC1 mediated purine sensing.
Zarou MM, Rattigan KM, Sarnello D, Shokry E, Dawson A, Ianniciello A, Dunn K, Copland M, Sumpton D, Vazquez A, Helgason GV.
Zarou MM, et al.
Nat Commun. 2024 Mar 2;15(1):1931. doi: 10.1038/s41467-024-46114-0.
Nat Commun. 2024.
PMID: 38431691
Free PMC article.
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Leukaemia exposure alters the transcriptional profile and function of BCR::ABL1 negative macrophages in the bone marrow niche.
Dawson A, Zarou MM, Prasad B, Bittencourt-Silvestre J, Zerbst D, Himonas E, Hsieh YC, van Loon I, Blanco GR, Ianniciello A, Kerekes Z, Krishnan V, Agarwal P, Almasoudi H, McCluskey L, Hopcroft LEM, Scott MT, Baquero P, Dunn K, Vetrie D, Copland M, Bhatia R, Coffelt SB, Tiong OS, Wheadon H, Zanivan S, Kirschner K, Helgason GV.
Dawson A, et al. Among authors: zarou mm.
Nat Commun. 2024 Feb 5;15(1):1090. doi: 10.1038/s41467-024-45471-0.
Nat Commun. 2024.
PMID: 38316788
Free PMC article.
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ULK1 inhibition promotes oxidative stress-induced differentiation and sensitizes leukemic stem cells to targeted therapy.
Ianniciello A, Zarou MM, Rattigan KM, Scott M, Dawson A, Dunn K, Brabcova Z, Kalkman ER, Nixon C, Michie AM, Copland M, Vetrie D, Ambler M, Saxty B, Helgason GV.
Ianniciello A, et al. Among authors: zarou mm.
Sci Transl Med. 2021 Sep 29;13(613):eabd5016. doi: 10.1126/scitranslmed.abd5016. Epub 2021 Sep 29.
Sci Transl Med. 2021.
PMID: 34586834
Free PMC article.
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